Prevention of renal injury after induction of ozone tolerance in rats submitted to warm ischaemia.

Prevention of renal injury after induction of ozone tolerance in rats submitted to warm ischaemia.

Prevention of renal injury after induction of ozone tolerance in rats submitted to warm ischaemia.

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Abstract

On the basis that ozone (O3) can upregulate cellular antioxidant enzymes, a morphological, biochemical and functional renal study was performed in rats undergoing a prolonged treatment with O3 before renal ischaemia. Rats were divided into four groups: (1) control, a medial abdominal incision was performed to expose the kidneys; (2) ischaemia, in animals undergoing a bilateral renal ischaemia (30 min), with subsequent reperfusion (3 h); (3) O3 + ischaemia, as group 2, but with previous treatment with O3 Login to read more

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